Chlamydia pneumoniae infection induces inflammatory changes in the aortas of rabbits.

  title={Chlamydia pneumoniae infection induces inflammatory changes in the aortas of rabbits.},
  author={Kirsi Laitinen and Aino Laurila and L Pyh{\"a}l{\"a} and Mika Leinonen and Pekka Saikku},
  journal={Infection and immunity},
  volume={65 11},
Chlamydia pneumoniae, a common human respiratory pathogen, has been associated with atherosclerosis in several seroepidemiological studies. Moreover, its presence in lesions of vessel walls has been demonstrated by culture, immunohistochemistry, PCR, and electron microscopy. In this study, we infected intranasally with C. pneumoniae New Zealand White rabbits which had been fed a normal diet. Reinfection was given 3 weeks later. Six of the nine reinfected animals showed inflammatory changes… CONTINUE READING


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