Chlamydia pneumoniae Multiply in Neutrophil Granulocytes and Delay Their Spontaneous Apoptosis1

@article{vanZandbergen2004ChlamydiaPM,
  title={Chlamydia pneumoniae Multiply in Neutrophil Granulocytes and Delay Their Spontaneous Apoptosis1},
  author={Ger van Zandbergen and Jens Gieffers and Henning Kothe and Jan Rupp and Annalena Bollinger and Eresso Aga and Matthias Klinger and Helmut Brade and Klaus Dalhoff and Matthias Maass and W Solbach and Tam{\'a}s Laskay},
  journal={The Journal of Immunology},
  year={2004},
  volume={172},
  pages={1768 - 1776}
}
The obligate intracellular bacterial pathogen Chlamydia pneumoniae (Cp) is responsible for a range of human diseases, including acute respiratory infection. Although experimental intratracheal infection with Cp results in a massive recruitment of neutrophil granulocytes (polymorphonuclear neutrophils (PMN)), the role of these cells in the defense against Cp is unclear. In this study the interactions of PMN with Cp were investigated. In vitro coincubation experiments showed that human… Expand
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