Chlamydia outer membrane protein discovery using genomics.

@article{Stephens2001ChlamydiaOM,
  title={Chlamydia outer membrane protein discovery using genomics.},
  author={Richard S. Stephens and Claudia J. Lammel},
  journal={Current opinion in microbiology},
  year={2001},
  volume={4 1},
  pages={
          16-20
        }
}
Outer membrane proteins of microbial pathogens serve essential roles in engaging the host environment and can be important immunotherapeutic targets. Because of the difficulty of growing large quantities of chlamydiae suitable for biochemical fractionation, little was known about their outer membrane protein composition prior to the recent sequencing of the C. trachomatis and C. pneumoniae genomes. Using bioinformatic approaches to characterize chlamydial open reading frames, novel outer… CONTINUE READING
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