Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.

@article{Coers2008ChlamydiaME,
  title={Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.},
  author={J{\"o}rn Coers and Isaac Bernstein-Hanley and David A. Grotsky and Iana Angelova Parvanova and Jonathan Charles Howard and Gregory Alan Taylor and William F. Dietrich and Michael N. Starnbach},
  journal={Journal of immunology},
  year={2008},
  volume={180 9},
  pages={
          6237-45
        }
}
Chlamydiae are obligate intracellular bacterial pathogens that exhibit a broad range of host tropism. Differences in host tropism between Chlamydia species have been linked to host variations in IFN-gamma-mediated immune responses. In mouse cells, IFN-gamma can effectively restrict growth of the human pathogen Chlamydia trachomatis but fails to control growth of the closely related mouse pathogen Chlamydia muridarum. The ability of mouse cells to resist C. trachomatis replication is largely… CONTINUE READING
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