Chlamydia muridarum Alters the Immune Environment of the Murine Genital Tract to be More Permissive for Infection with Neisseria gonorrhoeae in a Novel Coinfection Model

@inproceedings{Vonck2011ChlamydiaMA,
  title={Chlamydia muridarum Alters the Immune Environment of the Murine Genital Tract to be More Permissive for Infection with Neisseria gonorrhoeae in a Novel Coinfection Model},
  author={Rachel A. Vonck},
  year={2011}
}
Abstract : Coinfection with Neisseria gonorrhoeae and Chlamydia trachomatis occurs frequently, yet studies of the interaction between these two pathogens within the host have been hindered by the lack of an experimental model. Here we describe development and characterization of a female mouse model of gonococcal and chlamydial coinfection. BALB/c mice were first infected with C. muridarum, the mouse chlamydiae, and then inoculated with N. gonorrhoeae following estradiol treatment to promote… CONTINUE READING

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