Chlamydia Vaccine Development

  title={Chlamydia Vaccine Development},
  author={Joseph U. Igietseme and Carolyn M. Black},
The search for a safe and efficacious human chlamydial vaccine has been ongoing for more than 5 decades. Unfortunately, the dream has yet to be realized. However, much progress has been made in defining the immunologic requirements of a potentially efficacious vaccine, which involve the induction of a strong CD4 T cell-driven Th1 response, as well as an accessory antibody response that is vital for a rapid and robust memory response to reinfections. While a subunit vaccine is currently… CONTINUE READING

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