Chitosan films: a potential local drug delivery system for antibiotics.

  title={Chitosan films: a potential local drug delivery system for antibiotics.},
  author={Scott P Noel and Harry S Courtney and Joel D. Bumgardner and Warren O. Haggard},
  journal={Clinical orthopaedics and related research},
  volume={466 6},
Local antibiotic delivery is an emerging area of study designed to provide alternative methods of treatment to clinicians for compromised wound sites where avascular zones can prevent the delivery of antibiotics to the infected tissue. Antibiotic-loaded bone cement is the gold standard for drug-eluting local delivery devices but is not ideal because it requires a removal surgery. Chitosan is a biocompatible, biodegradable polymer that has been used in several different drug delivery… CONTINUE READING