Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties.

@article{Trifkovi2015ChitosanCM,
  title={Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties.},
  author={Kata T. Trifkovi{\'c} and Nikola Z. Mila{\vs}inovi{\'c} and Verica B Djordjevi{\'c} and Gordana M Zduni{\'c} and Melina T Kalagasidis Kru{\vs}i{\'c} and Zorica D. Kne{\vz}evi{\'c}-Jugovi{\'c} and Katarina P {\vS}avikin and Viktor A Nedovi{\'c} and Branko M. Bugarski},
  journal={Journal of biomaterials applications},
  year={2015},
  volume={30 5},
  pages={618-31}
}
Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on water and polyphenols transport properties was investigated. Swelling ratio of dry particles (68-230 µm) in water ranged from 280% to 530%, depending on the formulation. The decrease… CONTINUE READING