Chitosan-based thermosensitive hydrogel containing liposomes for sustained delivery of cytarabine.

@article{Mulik2009ChitosanbasedTH,
  title={Chitosan-based thermosensitive hydrogel containing liposomes for sustained delivery of cytarabine.},
  author={Rohit Mulik and Vijay R Kulkarni and Rayasa S. Ramchandra Murthy},
  journal={Drug development and industrial pharmacy},
  year={2009},
  volume={35 1},
  pages={49-56}
}
Sustained release thermosensitive solution containing cytarabine-loaded liposome delivery system offers the possibility of reduced dosing frequency and sustained drug action. Biodegradable and biocompatible chitosan-beta-glycerophosphate (C-GP) thermosensitive solution having the property to gel at body temperature and to maintain its physical integrity for longer period of time was used. The C-GP solution containing cytarabine-loaded liposomes (CGPCLL) was studied, and the results showed that… CONTINUE READING

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