Chitosan based nanoparticles functionalized with peptidomimetic derivatives for oral drug delivery.

@article{Chronopoulou2016ChitosanBN,
  title={Chitosan based nanoparticles functionalized with peptidomimetic derivatives for oral drug delivery.},
  author={Laura Chronopoulou and Giuseppina Nocca and Massimo Castagnola and G. Paludetti and Giancarlo Ortaggi and Fabio Sciubba and Melania Bevilacqua and Alessandro Lupi and Gianluca Gambarini and Cleofe Palocci},
  journal={New biotechnology},
  year={2016},
  volume={33 1},
  pages={23-31}
}
The goal of this study was to develop an optimized drug delivery carrier for oral mucosa applications able to release in situ bioactive molecules by using biopolymeric materials. Among them chitosan and poly(lactic-co-glycolic acid) (PLGA) have gained considerable attention as biocompatible carriers able to improve the delivery of active agents. The formulation of such vehicles in the form of nanoparticles (NPs) could permit to exploit the peculiar properties of nanomaterials in order to… CONTINUE READING
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