Chitosan/alginate multilayer film for controlled release of IDM on Cu/LDPE composite intrauterine devices.

@article{Tian2013ChitosanalginateMF,
  title={Chitosan/alginate multilayer film for controlled release of IDM on Cu/LDPE composite intrauterine devices.},
  author={Kuan Tian and Changsheng Xie and Xianping Xia},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2013},
  volume={109},
  pages={
          82-9
        }
}
To reduce such side effects as pain and bleeding caused by copper-containing intrauterine device (Cu-IUD), a novel medicated intrauterine device, which is coated with an indomethacin (IDM) delivery system on the surface of copper/low-density polyethylene (Cu/LDPE) composite intrauterine device, has been proposed and developed in the present work. The IDM delivery system is a polyelectrolyte multilayer film, which is composed of IDM containing chitosan and alginate layer by layer, is prepared by… CONTINUE READING
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