Chitinase-like proteins are candidate biomarkers for sepsis-induced acute kidney injury.

@article{Maddens2012ChitinaselikePA,
  title={Chitinase-like proteins are candidate biomarkers for sepsis-induced acute kidney injury.},
  author={Bert E J Maddens and Bart Ghesqui{\`e}re and Raymond Camille Vanholder and Dieter Demon and Jill Vanmassenhove and Kris Gevaert and Evelyne Meyer},
  journal={Molecular & cellular proteomics : MCP},
  year={2012},
  volume={11 6},
  pages={M111.013094}
}
Sepsis-induced acute kidney injury (AKI) is a frequent complication of critically ill patients and leads to high mortality rates. The specificity of currently available urinary biomarkers for AKI in the context of sepsis is questioned. This study aimed to discover urinary biomarkers for septic AKI by contemporary shotgun proteomics in a mouse model for sepsis and to validate these in individual urine samples of mice and human septic patients with and without AKI. At 48 h after uterine ligation… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS