Chitin regulation of immune responses: an old molecule with new roles.

@article{Lee2008ChitinRO,
  title={Chitin regulation of immune responses: an old molecule with new roles.},
  author={Chun Geun Lee and Carla Graziele Azevedo da Silva and Jae-young Lee and Dominik Hartl and Jack A Elias},
  journal={Current opinion in immunology},
  year={2008},
  volume={20 6},
  pages={684-9}
}
Chitin, the second most abundant polysaccharide in nature, is commonly found in lower organisms such as fungi, crustaceans, and insects, but not in mammals. Although the non-specific anti-viral and anti-tumor activities of chitin/chitin derivatives were described two decades ago, the immunological effects of chitin have been only recently been addressed. Recent studies demonstrated that chitin has complex and size-dependent effects on innate and adaptive immune responses including the ability… CONTINUE READING