Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis

@article{Liberti2017ChitinPT,
  title={Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis},
  author={Assunta Liberti and Ivana Zucchetti and Daniela Melillo and Diana P. Skapura and Yoshimi Shibata and Rosaria De Santis and Maria Rosaria Pinto and Gary W. Litman and Larry J Dishaw},
  journal={Biology Open},
  year={2017},
  volume={7}
}
The gastrointestinal tract of Ciona intestinalis, a solitary tunicate that siphon-filters water, shares similarities with its mammalian counterpart. [] Key Result Exposure of Ciona to dextran sulphate sodium (DSS) induces a colitis-like phenotype similar to that seen in other systems, and is characterized by alteration of epithelial morphology and infiltration of blood cells into lamina propria-like regions.
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