Chitin and Its Effects on Inflammatory and Immune Responses

@article{EliehAliKomi2017ChitinAI,
  title={Chitin and Its Effects on Inflammatory and Immune Responses},
  author={Daniel Elieh Ali Komi and Lokesh Sharma and Charles S. Dela Cruz},
  journal={Clinical Reviews in Allergy \& Immunology},
  year={2017},
  volume={54},
  pages={213-223}
}
Chitin, a potential allergy-promoting pathogen-associated molecular pattern (PAMP), is a linear polymer composed of N-acetylglucosamine residues which are linked by β-(1,4)-glycosidic bonds. Mammalians are potential hosts for chitin-containing protozoa, fungi, arthropods, and nematodes; however, mammalians themselves do not synthetize chitin and thus it is considered as a potential target for recognition by mammalian immune system. Chitin is sensed primarily in the lungs or gut where it… 
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