• Corpus ID: 75973959

Chiropractic and the Neuroimmune Connection

  title={Chiropractic and the Neuroimmune Connection},
  author={Ari Cohn},
Objective: To review the literature on the connections between the nervous and the immune systems, and to explore the contention that chiropractic adjustments may affect neuroimmune function. Data Collection: Relevant articles in English were retrieved through a search of MEDLINE and the Index to Chiropractic Literature. Key search terms included: chiropractic, immune system, nervous system, sympathetic nervous system. Articles were included if they discussed or tested the chemical or… 
Improvement in Cystic Fibrosis in a Child Undergoing Subluxation-Based Chiropractic Care: A Case Study
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The conservative chiropractic care of a child with chronic sinusitis, constipation, and sore throat showed improvement of symptoms over a three month period.
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This case demonstrates a link between chiropractic subluxation management and improvement of symptoms of Pervasive Developmental Disorder and Sensory Processing Disorder.
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Supporting evidence that chiropractic adjustments may improve immune system functioning is presented, thus relieving otitis media, adenoid hypertrophy, nasal congestion and their subsequent effects.


An overview of neuroimmunomodulation and a possible correlation with musculoskeletal system function.
There is an increasing body of evidence that the nervous system is capable of modulating the immune response and spinal manipulation can correct the spinal fixations and may eliminate the adverse affects of somatosympathetic reflexes.
The autonomic nervous system as a communication channel between the brain and the immune system.
The altered activities of the splenic sympathetic nerves have been found to be causally related to the alteration in immunological responses including natural killer cytotoxicity, and may constitute a communication channel that mediates central modulation of peripheral cellular immunity.
Evidence that thymosins and other biologic response modifiers can function as neuroactive immunotransmitters.
It is proposed that the term "immunotransmitter" be used to describe molecules that are produced predominantly by cells that comprise the immune system but that transmit specific signals and information to neurons and other cell types.
The psychosomatic network: foundations of mind-body medicine.
It is suggested that emotional expression generates balance in the neuropeptide-receptor network and a functional healing system, and is also a marker for psychospiritual vitalization.
The sympathetic nerve--an integrative interface between two supersystems: the brain and the immune system.
The activation of SNS during an immune response might be aimed to localize the inflammatory response, through induction of neutrophil accumulation and stimulation of more specific humoral immune responses, although systemically it may suppress Th1 responses, and, thus protect the organism from the detrimental effects of proinflammatory cytokines and other products of activated macrophages.
Somatovisceral aspects of chiropractic : an evidence-based approach
This chapter discusses somatovisceral functions that are activated or inhibited by somatic sensory stimulation, and how Chiropractic Care and the Cardiovascular System and Endocrine Disorders affect these functions.
Noradrenergic Sympathetic Neural Interactions with the Immune System: Structure and Function
It is proposed that NE in lymphoid organs fulfills the criteria for neurotransmission, estabUshed in more traditional efTector tissues such as the heart, and plays a role in the modulation of immune responses.
Peptide hormones shared by the neuroendocrine and immunologic systems.
These studies suggest that the immune and neuroendocrine systems represent a totally integrated circuit by virtue of sharing a common set of hormones, such as corticotropin, thyrotropin, and endorphins, and their receptors.
Sympathetic nervous system response to mechanical stress of the spinal column in rats.
  • A. Sato, R. Swenson
  • Biology, Medicine
    Journal of manipulative and physiological therapeutics
  • 1984
The present study has demonstrated potent somatovisceral reflexes from mechanical stimulation of the spinal column, which were found not to be due to spinal cord compression, but rather were ascribed to afferent fiber mediated reflexes.