Chiral-substrate-assisted stereoselective epoxidation catalyzed by H2O2-dependent cytochrome P450SPα.

Abstract

The stereoselective epoxidation of styrene was catalyzed by H(2) O(2) -dependent cytochrome P450(SPα) in the presence of carboxylic acids as decoy molecules. The stereoselectivity of styrene oxide could be altered by the nature of the decoy molecules. In particular, the chirality at the α-positions of the decoy molecules induced a clear difference in the… (More)
DOI: 10.1002/asia.201200250

Topics

Cite this paper

@article{Fujishiro2012ChiralsubstrateassistedSE, title={Chiral-substrate-assisted stereoselective epoxidation catalyzed by H2O2-dependent cytochrome P450SPα.}, author={Takashi Fujishiro and Osami Shoji and Norifumi Kawakami and Takahiro Watanabe and Hiroshi Sugimoto and Yoshitsugu Shiro and Yoshihito Watanabe}, journal={Chemistry, an Asian journal}, year={2012}, volume={7 10}, pages={2286-93} }