Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC.

  title={Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC.},
  author={Imran Ali and Vinay D Gaitonde and Hassan Y Aboul-Enein and Afzal Hussain},
  volume={78 2},
The chiral separation of 10 beta-adrenergic blockers (acebutalol, alprenolol, bufuralol, bisoprolol, celiprolol, carazolol, indenolol, metoprolol, oxprenolol and propranolol) was achieved on CelluCoat column (250 mm x 4.6mm, 5 microm particle size). The mobile phases used were (90:10:0.2, v/v/v) and (95:5:0.2, v/v/v) combinations of n-heptane-ethanol-diethylamine, respectively. The flow rates were 0.5, 1.0 and 2.0 mL min(-1) with detection at 225 nm. The capacity (k), selectivity (alpha) and… CONTINUE READING
12 Extracted Citations
7 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 12 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-7 of 7 references

Chiral Separation by Liquid Chromatography and Related Technologies

  • H. Y. Aboul-Enein, I. Ali
  • Marcel Dekker Inc., New York, USA
  • 2003
Highly Influential
4 Excerpts


  • I. Ali, A. Hussain, H. Y. Aboul-Enein, G. Bazylak
  • Drug Discovery Technol. 4
  • 2007
1 Excerpt


  • H. Navratilova, R. Opatrilova, Z. Kriz
  • Koca, Chirality 16
  • 2004

Chromatographic Enantioseparation: Methods and Applications

  • S. Allenmark
  • Ellis Horwood Ltd., New York, USA
  • 1991
1 Excerpt

Chiral Separations

  • D. Stevenson, I. D. Wilson
  • Plenum Press, New York, USA
  • 1988
1 Excerpt


  • T. Walle, U. K. Walle, M. J. Wilson, T. C. Fagan, T. E. Gaffney
  • J. Clin. Pharmacol. 18
  • 1984
1 Excerpt

Review of Medical Pharmacology

  • E. H. Meyers, E. Jawetz, A. A. Goldheim
  • Lange Medical Publication, Los Altos, USA
  • 1980

Similar Papers

Loading similar papers…