Chiral separation of atropine by high-performance liquid chromatography.

  title={Chiral separation of atropine by high-performance liquid chromatography.},
  author={David Breton and David Buret and Pascal Clair and Michel Lafosse},
  journal={Journal of chromatography. A},
  volume={1088 1-2},
The separation and quantitation of the enantiomers and also the determination of the enantiomeric purity are now current and indispensable tasks for the pharmaceutical analysis. Among the various techniques, liquid chromatography remains the best modality owing to several advantages. High speed, sensitivity, and reproducible results make LC the method of choice in almost all laboratories. Phases that contain alpha1-acid glycoprotein as chiral selector are suitable for separation of charged and… CONTINUE READING