Chiral ligand derived from (1S,2R)-norephedrine as a catalyst for enantioselective prochiral ketone reduction

@inproceedings{Balakrishnan2009ChiralLD,
  title={Chiral ligand derived from (1S,2R)-norephedrine as a catalyst for enantioselective prochiral ketone reduction},
  author={Umesh Balakrishnan and Nallamuthu Ananthi and Sivan Velmathi},
  year={2009}
}
Abstract Chiral oxazaborolidines derived from (1 S ,2 R )-(+)-norephedrine and substituted salicylaldehydes were employed in the asymmetric reduction of prochiral ketones using borane dimethyl sulfide as a reducing agent. The secondary alcohols were formed in excellent yields (45–99.8%) with enantioselectivities up to 99.8%. The effect of the substitution in the aromatic ring of the ligand was discussed with the enantioselectivity of the product.