Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease

  title={Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease},
  author={Tomonori Kimura and Kenji Hamase and Yurika Miyoshi and Ryohei Yamamoto and Keiko Yasuda and Masashi Mita and Hiromi Rakugi and Terumasa Hayashi and Yoshitaka Isaka},
  booktitle={Scientific reports},
D-Amino acids, the enantiomers of L-amino acids, are increasingly recognized as novel biomarkers. Although the amounts of D-amino acids are usually very trace in human, some of them have sporadically been detected in blood from patients with kidney diseases. This study examined whether multiple chiral amino acids would be associated with kidney functions, comorbidities, and prognosis of chronic kidney disease (CKD) by enantioselective analyses of all chiral amino acids with a micro-two… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 44 references

Early Detection of Renal Dysfunction Using the Ratio of Serine Enantiomers

Sasabe, J. et al. Ischemic Acute Kidney Injury Perturbs Homeo Mice
PLoS ONE 9, e86504 • 2014

D-amino acid oxidase controls motoneuron degeneration through D-serine.

Proceedings of the National Academy of Sciences of the United States of America • 2012

Plasma B-type natriuretic peptide level predicts kidney prognosis in patients with predialysis chronic kidney disease.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 2012

D-Aspartate--an important bioactive substance in mammals: a review from an analytical and biological point of view.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences • 2011

Effects of chronic kidney disease and post-angiographic acute kidney injury on long-term prognosis after coronary artery angiography

T Kimura
Nephrol Dial Transplant • 2011

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