Chiral BINOL-derived phosphoric acids: privileged Brønsted acid organocatalysts for C-C bond formation reactions.


BINOL-derived phosphoric acids have emerged during the last five years as powerful chiral Brønsted acid catalysts in many enantioselective processes. The most successful transformations carried out with chiral BINOL phosphates include C-C bond formation reactions. The recent advances have been reviewed in this article with a focus being placed on hydrocyanations, aldol-type, Mannich, Friedel-Crafts, aza-ene-type, Diels-Alder, as well as cascade and multi-component reactions.

DOI: 10.1039/c0ob00209g

Cite this paper

@article{Zamfir2010ChiralBP, title={Chiral BINOL-derived phosphoric acids: privileged Br\onsted acid organocatalysts for C-C bond formation reactions.}, author={Alexandru Zamfir and Sebastian Schenker and Matthias Freund and Svetlana B. Tsogoeva}, journal={Organic & biomolecular chemistry}, year={2010}, volume={8 23}, pages={5262-76} }