Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development.

@article{Pueyo2004ChipmediatedPO,
  title={Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development.},
  author={Jos{\'e} Ignacio Pueyo and Juan Pablo Couso},
  journal={Development},
  year={2004},
  volume={131 13},
  pages={3107-20}
}
Proximodistal patterning in Drosophila requires division of the developing leg into increasingly smaller, discrete domains of gene function. The LIM-HOM transcription factors apterous (ap) and Lim1 (also known as dlim1), and the homeobox genes Bar and aristaless (al) are part of the gene battery required for the development of specific leg segments. Our genetic results show that there are posttranslational interactions between Ap, Bar and the LIM-domain binding protein Chip in tarsus four, and… CONTINUE READING

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HNF 3 B and Lim 1 interact in the visceral endoderm to regulate primitive streak formation and anterior - posterior polarity in the mouse embryo

  • J. I. Pueyo, M. I. Galindo, S. A. Bishop, J. P. Couso
  • Development
  • 2000
Highly Influential
20 Excerpts

of the Drosophila wing

  • M. Milan, F. J. Diaz-Benjumea, S. M. Cohen
  • 1998
Highly Influential
19 Excerpts

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