Chip based biosensor for functional analysis of single ion channels

  title={Chip based biosensor for functional analysis of single ion channels},
  author={Horst Vogel},
  • H. Vogel
  • Published 1 September 2000
  • Biology
The functional anal. of single ion channel proteins presents a serious bottleneck in the process of finding new pharmacol. active compds. Currently available single channel recording methods are not suited for automation and miniaturization. However, new techniques such as combinatorial chem. and combinatorial genetics, which produce large amts. of potential drugs and mutant proteins, demand efficient and reliable screening as well as low sample consumption. Here we present a novel, silicon… 

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