Chip-based array magnetic solid phase microextraction on-line coupled with inductively coupled plasma mass spectrometry for the determination of trace heavy metals in cells.

@article{Wang2015ChipbasedAM,
  title={Chip-based array magnetic solid phase microextraction on-line coupled with inductively coupled plasma mass spectrometry for the determination of trace heavy metals in cells.},
  author={H. Wang and Z. Wu and B. Chen and M. He and Bin Hu},
  journal={The Analyst},
  year={2015},
  volume={140 16},
  pages={
          5619-26
        }
}
Determination of trace elements in cells is critical to metallomics research and still faces tremendous difficulties even with the help of highly sensitive inductively coupled plasma mass spectrometry (ICP-MS). Microfluidic chips offer a functional tool-set for cell analysis with features of miniaturization, integration and automation. In this work, we proposed a chip-based array magnetic solid phase microextraction (MSPME) system and on-line combined it with ICP-MS via microflow concentric… Expand
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