• Corpus ID: 36841857

Chinese herbs: a clinical review of Astragalus, Ligusticum, and Schizandrae.

@article{Sinclair1998ChineseHA,
  title={Chinese herbs: a clinical review of Astragalus, Ligusticum, and Schizandrae.},
  author={Stephanie Sinclair},
  journal={Alternative medicine review : a journal of clinical therapeutic},
  year={1998},
  volume={3 5},
  pages={
          338-44
        }
}
  • S. Sinclair
  • Published 1 October 1998
  • Medicine, Biology
  • Alternative medicine review : a journal of clinical therapeutic
Although Astragalus, Ligusticum and Schizandrae have a long history of medicinal use within the traditional Chinese system, only recently has the West begun to understand their pharmacological possibilities and clinical applications. Astragalus has demonstrated a wide range of immunopotentiating effects and has proven efficacious as an adjunct cancer therapy. Ligusticum, and its active components, have been investigated for enhancement of the immune system, treatment of ischemic disorders, and… 

Figures from this paper

Recent progress in phytochemistry, pharmacology and biotechnology of Astragalus saponins
TLDR
Details on their structure, distribution, recent information on the pharmacological properties and biotechnology of Astragalus saponins will be summarized and thoroughly discussed.
The Role of Endophytic/Epiphytic Bacterial Constituents in the Immunostimulatory Activity of the Botanical, Astragalus membranaceus
TLDR
The results support that many immune enhancing botanicals have established a symbiotic relationship with Gram-negative bacteria and that the immune enhancing effect of these botanical extracts on the body may not only be due to endogenous plant compounds, but endophytic (or epiphytic) bacterial components as well.
Nutritional Support for the Immune System
TLDR
A review article examines 3 popular herbal immune stimulants that are often of interest to cancer patients and appears that the extracts shorten the duration and severity of colds and other upper respiratory infections when given as soon as symptoms become evident.
Astragalus species: Insights on its chemical composition toward pharmacological applications
TLDR
The aim of this work is to give a comprehensive summary of the Astragalus spp.
Bing de ling, a Chinese herbal formula, stimulates multifaceted immunologic responses in mice.
TLDR
It is found that bing de ling potentiates upregulation of immune activity when administered to mice in dosages proportional to those used clinically, and is identified as a promising candidate for clinical trials against diverse diseases that may respond to increased immunologic activity.
Genotoxicity Study of Polysaccharide Fraction from Astragalus membranaceus's Aerial Parts
TLDR
Genotoxicity assays provided strong overall support that the crude polysaccharide fraction lacks mutagenic and/or clastogenic potential under the GLP-based test conditions, indicating the aerial parts of A. membranaceus would be safe enough for a food material and a dietary supplement.
Advances in phytochemistry, pharmacology and biotechnology of Bulgarian Astragalus species
TLDR
This review is focused on phytochemical, pharmacological and biotechnological studies of Bulgarian Astragalus plants and includes also results from the authors' investigations.
Malva species: Insights on its chemical composition towards pharmacological applications
TLDR
Results from in vitro and in vivo experiments encourage more in‐depth studies, namely clinical trials, towards to improve knowledge on the use of Malva spp.
Comprehensive evaluation of two Astragalus species (A. campylosema and A. hirsutus) based on biological, toxicological properties and chemical profiling.
...
...

References

SHOWING 1-10 OF 34 REFERENCES
Pharmacological actions and clinical use of fructus schizandrae.
TLDR
Results indicated that FS and its several components can mainly protect liver from injury induced by toxic substances such as CCl4; they have anti-oxidant activities against oxygen free radicals and promote certain anabolic metabolism such as serum protein biosynthesis and glycogenesis.
[Effects of mixture of Astragalus membranaceus, Fructus Ligustri lucidi and Eclipta prostrata on immune function in mice].
  • J. He, Y. Li, S. Wei, M. Guo, W. Fu
  • Biology
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao
  • 1992
TLDR
AFE turned out a resistance to the immunosuppressive effect caused by cyclophosphamide and could obviously raise the conversion percentage of lymphocytes and serum IgG level of mice.
Bioactivity of neolignans from fructus Schizandrae.
  • X. Li
  • Biology, Chemistry
    Memorias do Instituto Oswaldo Cruz
  • 1991
TLDR
It was found that some principles of Schizandrae have an inducing effect on hepatic microsomal drug-metabolizing enzyme system P-450, thus explained their anti-toxic, anti-carcinogenic and anti-mutagenic effects.
Antiinflammatory effect of tetramethylpyrazine and ferulic acid.
  • Y. Ozaki
  • Chemistry
    Chemical & pharmaceutical bulletin
  • 1992
TLDR
It is suggested that both compounds have the antiinflammatory effect and the analgesic effect, and both compounds exert an anti inflammatory effect at the early and the late stages of processes in the inflammatory pathology.
Ischemic stroke treated with Ligusticum chuanxiong.
TLDR
The results showed that the effects of the drugs were the same as or even better than those of the controls, such as papaverine, dextran and aspirin-persantin.
[Clinical observation on the treatment of ischemic heart disease with Astragalus membranaceus].
  • S. Li, R. Yuan, H. Gao
  • Medicine
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
  • 1995
TLDR
The treatment of ischemic heart disease with AM was significantly more effective in comparing with control group (P < 0.05); the improvement of clinical objective index such as electrocardiogram (EKG) and impedance cardiogram can also be observed.
[Effect of Astragalan on secretion of tumor necrosis factors in human peripheral blood mononuclear cells].
  • K. Zhao, H. Kong
  • Biology, Medicine
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
  • 1993
TLDR
After isolation of adherent and nonadherent mononuclear cells from PBMC, Astragalan increased the secretion of TNF-alpha and T NF-beta respectively, and these results suggest further study of AStragalan would promote the application of ASTRagalan in cancer immunotherapy.
[Effect of Astragalus membranaceus on T-lymphocyte subsets in patients with viral myocarditis].
  • Z. Huang, N. Qin, W. Ye
  • Medicine, Biology
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
  • 1995
TLDR
The results showed that the T-lymphocyte subsets profile and OKT4/OKT8 ratio of peripheral blood were significantly lower in viral myocarditis patients than that in healthy control.
[Phytotherapeutic aspects of diseases of the cardiovascular system. 5. Saponins and possibilities of their use in prevention and therapy].
  • J. Purmova, L. Opletal
  • Medicine, Biology
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti
  • 1995
TLDR
It can be concluded that saponins are a prospective group of drugs of natural origin for the prevention and treatment of diseases of the heart and circulatory system.
...
...