Chinese herbal medicine for idiopathic sudden sensorineural hearing loss: a systematic review of randomised clinical trials

  title={Chinese herbal medicine for idiopathic sudden sensorineural hearing loss: a systematic review of randomised clinical trials},
  author={Chunxiang Su and L.‐J. Yan and George Lewith and J-P Liu},
  journal={Clinical Otolaryngology},
  pages={455 - 473}
Idiopathic sudden sensorineural hearing loss has great impact on quality of life. Many clinical trials using Chinese herbal medicine for idiopathic sudden sensorineural hearing loss have been conducted and reported beneficial results. However, there is no critical appraised evidence on efficacy and safety of Chinese herbal medicine for idiopathic sudden sensorineural hearing loss to inform clinical use. 

Acupuncture Therapy for Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

There was not sufficient evidence showing that acupuncture therapy alone was beneficial for treating SSHL, however, interventions combining acupuncture with WMCT had more efficacious results in the treatment of SSHL than WMCT alone.

Clinical management and progress in sudden sensorineural hearing loss during pregnancy

Although some patients have a tendency for self-cure, treatment with intravenous dextran 40 combined with intratympanic corticosteroids is probably a safe and effective therapeutic strategy for pregnant patients with SSNHL.

Current Research in Acupuncture Treatment for Sudden Sensorineural Hearing Loss

A research showed an association of genes related to prothrombotic states and promoted serum levels of fibrinogen and homocysteine in patients with SSNHL offered a multifactorial basis for microvascular events as a cause ofSSNHL.

Clinical Practice Guideline: Sudden Hearing Loss (Update)

This guideline update is intended for all clinicians who diagnose or manage adult patients who present with sudden hearing loss and should improve diagnostic accuracy, facilitate prompt intervention, decrease variations in management, reduce unnecessary tests and imaging procedures, and improve hearing and rehabilitative outcomes for affected patients.

The effect of berberine on insulin resistance in women with polycystic ovary syndrome: detailed statistical analysis plan (SAP) for a multicenter randomized controlled trial

This randomized controlled trial aims to evaluate the efficacy and safety of berberine in the treatment of patients with polycystic ovary syndrome and prepared this statistical analysis plan (SAP).

Role of Oxidative Stress and Antioxidants in Acquired Inner Ear Disorders

This review focuses on the relationship between acquired hearing loss and antioxidant use to provide an overview of novel antioxidants, namely medicines, supplemental nutrients, and natural foods, based on clinical, animal, and cultured-cell studies.

Methodological Quality of Systematic Reviews and Meta-analyses Published in High-Impact Otolaryngology Journals

Intervention-focused systematic reviews and meta-analyses published in high-impact otolaryngology journals have important methodological limitations that diminish confidence in the results of these reviews.

Hipoacusia neurosensorial súbita, el gran dilema de la otorrinolaringología. Una revisión de la literatura

Introducción La hipoacusia neurosensorial súbita es una emergencia otorrinolaringológica descrita desde 1944 y que continúa siendo un gran enigma. El objetivo es resumir e identificar los aspectos



Sudden sensorineural hearing loss: etiologies and treatments.

  • M. ThurmondR. Amedee
  • Medicine
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society
  • 1998
This review of sudden hearing loss will focus on the three main etiologic theories and numerous treatments studied in recent years in order to better enable clinicians to understand, diagnose, and treat the disorder.

Clinical practice. Idiopathic sudden sensorineural hearing loss.

  • S. Rauch
  • Medicine
    The New England journal of medicine
  • 2008
A healthy 58-year-old woman answers the telephone and realizes that her hearing is diminished on the left side. She notices aural fullness and loud tinnitus in the affected ear. Self-administered ear

Aanalysis of the Sudden Hearing Loss in 60 Patients

The integrated therapy with Western and Chinese Medicines is effective on sudden hearing loss and is worth to be used in clinic practice.

Quality of Life in Patients With Idiopathic Sudden Hearing Loss: Comparison of Different Therapies Using the Medical Outcome Short Form (36) Health Survey Questionnaire

  • R. MösgesJ. KöberleinB. ErdtrachtR. Klingel
  • Medicine, Psychology
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • 2008
Quality of life measured in Medical Outcome Short Form (36) Health Survey scores was less than the level of the normal German population at baseline for all groups, and mentally, ISHL patients felt more impaired than patients who have chronic hearing impairment.

Clinical Practice Guideline: Sudden Hearing Loss

The panel will discuss the newly developed AAO-HNS clinical practice guideline to improve the diagnosis and management of sudden hearing loss in adults aged 18 years and older.

Diagnosis and treatment of idiopathic sudden sensorineural hearing loss (ISSHL). A survey in The Netherlands and Flanders.

A survey on diagnosis and treatment of Idiopathic Sudden Sensorineural Hearing Loss (ISSHI) and report the opinion of 230 Dutch and 50 Flemish ENT-surgeons found shortcomings in diagnosis of ISSHL and recommend the use of a diagnostic protocol based on a differential diagnosis.

Clinical observation on the therapeutic effects of an integrative medicine therapy on the accompanied tinnitus and vertigo with sudden deafness

IMT is more effective in the symptom improving, like tinnitus, accompanied with sudden deafness, than CG, and these two rates were significantly higher in TG than in CG.

Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss.

The effectiveness of vasodilators in the treatment of ISSHL remains unproven due to the degree of heterogeneity, and only three trials, involving 189 participants, satisfied the inclusion criteria and these were of low methodological quality.

Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus.

There is no evidence of a beneficial effect of HBOT on chronic presentation of ISSHL and/or tinnitus and it is recommended not to recommend use ofHBOT for this purpose based on the single study available.

Antivirals for idiopathic sudden sensorineural hearing loss.

Evidence from the four RCTs has demonstrated no statistically significant advantage in the use of antivirals in the treatment of ISSHL, and meta-analysis was not possible due to differing treatment protocols of varying dose and duration.