Evolutionary Traits and Genomic Surveillance of SARS-CoV-2 in South America
- BiologyGlobal Health
The lack of updated knowledge in South America justifies the need to develop a structured genomic surveillance program of current and emerging SARS-CoV-2 variants, and the modeling of the molecular events and microevolution of the virus will contribute to making better decisions on public health management of the pandemic and developing accurate treatments and more efficient vaccines.
COVID-19: Unmasking Emerging SARS-CoV-2 Variants, Vaccines and Therapeutic Strategies
- Biology, MedicineBiomolecules
There is convincing evidence of increased susceptibility to SARS-CoV-2 infection among individuals with dysregulated immune response and comorbidities, which provides a comprehensive perspective regarding vulnerability of Sars-CoVs infection in patients with underlying medical comorbridities.
Development of the Inactivated QazCovid-in Vaccine: Protective Efficacy of the Vaccine in Syrian Hamsters
- Biology, MedicinebioRxiv
The candidate vaccine suppressed the replication of the wild virus in the body of vaccinated hamsters, protected against the development of acute pneumonia and ensured 100% survival of the animals.
Immune Evasive Effects of SARS-CoV-2 Variants to COVID-19 Emergency Used Vaccines
- BiologyFrontiers in Immunology
The prevalence and biological structure of these variants and the efficacy of currently used vaccines against the SARS-CoV-2 variants are summarized to provide guidance on how to design vaccines more rationally against the variants.