Chimpanzee Down syndrome: a case study of trisomy 22 in a captive chimpanzee

@article{Hirata2017ChimpanzeeDS,
  title={Chimpanzee Down syndrome: a case study of trisomy 22 in a captive chimpanzee},
  author={Satoshi Hirata and Hirohisa Hirai and Etsuko Nogami and Naruki Morimura and Toshifumi Udono},
  journal={Primates},
  year={2017},
  volume={58},
  pages={267-273}
}
We report a case of chimpanzee trisomy 22 in a captive-born female. Because chromosome 22 in great apes is homologous to human chromosome 21, the present case is analogous to human trisomy 21, also called Down syndrome. The chimpanzee in the present case experienced retarded growth; infantile cataract and vision problems, including nystagmus, strabismus, and keratoconus; congenital atrial septal defect; and hypodontia. All of these symptoms are common in human Down syndrome. This case was the… 
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