Chimeric virus-like particle formation of adeno-associated virus.

  title={Chimeric virus-like particle formation of adeno-associated virus.},
  author={Md Tozammel Hoque and Nobuyoshi Shimizu and Ken-ichiro Ishizu and Haruaki Yajima and Fumio Arisaka and Kaori Suzuki and Hajime Watanabe and Hiroshi Handa},
  journal={Biochemical and biophysical research communications},
  volume={266 2},
Adeno-associated virus (AAV) capsids are composed of three proteins, VP1, VP2, and VP3. These capsid proteins have a common amino acid sequence, being expressed from different initiation codons on the same open reading frame. Although VP1 is necessary for viral infection, it is not essential for capsid formation. The other capsid proteins, VP2 and VP3, are… CONTINUE READING