Chimeric smooth muscle-specific enhancer/promoters: valuable tools for adenovirus-mediated cardiovascular gene therapy.

@article{Ribault2001ChimericSM,
  title={Chimeric smooth muscle-specific enhancer/promoters: valuable tools for adenovirus-mediated cardiovascular gene therapy.},
  author={S{\'e}bastien Ribault and Pascal Neuville and Agn{\`e}s M{\'e}chine-Neuville and Fabrice Aug{\'e} and Ara Parlakian and Giulio Gabbiani and Denise Paulin and Val{\'e}rie Calenda},
  journal={Circulation research},
  year={2001},
  volume={88 5},
  pages={468-75}
}
Gene transfer with adenoviral vectors is an attractive approach for the treatment of atherosclerosis and restenosis. However, because expression of a therapeutic gene in nontarget tissues may have deleterious effects, artery-specific expression is desirable. Although expression vectors containing transcriptional regulatory elements of genes expressed solely… CONTINUE READING