Chimeric glycosyltransferases for the generation of hybrid glycopeptides.

Abstract

Glycodiversification, an invaluable tool for generating biochemical diversity, can be catalyzed by glycosyltransferases, which attach activated sugar "donors" onto "acceptor" molecules. However, many glycosyltransferases can tolerate only minor modifications to their native substrates, thus making them unsuitable tools for current glycodiversification… (More)
DOI: 10.1016/j.chembiol.2009.04.013

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