Chimeric antigen receptors: a costimulatory boost promotes immunological memory to B-cell malignancies.

  • Karl S. Peggs
  • Published 2011 in Expert review of anticancer therapy

Abstract

Cellular immunotherapies offer perhaps the best proof of concept of the ability of immune cells to eradicate malignancy. However, the majority of these data derive from either the use of expanded tumor-infiltrating lymphocytes to treat metastatic melanoma or the use of donor lymphocytes in relapsed hematological malignancies following allogeneic… (More)
DOI: 10.1586/era.11.159

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