Chimeric Coupling Proteins Mediate Transfer of Heterologous Type IV Effectors through the Escherichia coli pKM101-Encoded Conjugation Machine.

Abstract

UNLABELLED Bacterial type IV secretion systems (T4SSs) are composed of two major subfamilies, conjugation machines dedicated to DNA transfer and effector translocators for protein transfer. We show here that the Escherichia coli pKM101-encoded conjugation system, coupled with chimeric substrate receptors, can be repurposed for transfer of heterologous… (More)
DOI: 10.1128/JB.00378-16

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Cite this paper

@article{Whitaker2016ChimericCP, title={Chimeric Coupling Proteins Mediate Transfer of Heterologous Type IV Effectors through the Escherichia coli pKM101-Encoded Conjugation Machine.}, author={Neal Whitaker and Trista M Berry and Nathan Rosenthal and Jay E Gordon and Christian Gonz{\'a}lez-Rivera and Kathy B. Sheehan and Hilary K. Truchan and Lauren Viebrock and Irene L G Newton and Jason A Carlyon and Peter J Christie}, journal={Journal of bacteriology}, year={2016}, volume={198 19}, pages={2701-18} }