Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications

  title={Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications},
  author={John Read and Jim van Os and Anthony P Morrison and Craig A. Ross},
  journal={Acta Psychiatrica Scandinavica},
  • J. ReadJ. Os C. Ross
  • Published 1 November 2005
  • Psychology, Medicine
  • Acta Psychiatrica Scandinavica
Objective:  To review the research addressing the relationship of childhood trauma to psychosis and schizophrenia, and to discuss the theoretical and clinical implications. 

The effects of childhood trauma in patients with first‐episode schizophrenia

Evaluating the impact of childhood trauma on psychopathology in patients with first‐episode schizophrenia finds that childhood trauma has an important role in shaping adult psychopathology.


  • Psychology, Medicine
  • 2019
DISSOCIATIVE SYMPTOMS in PATIENTS with SCHIZOPHRENIA and their association with childhood trauma and their associations with substance abuse rehabilitation are studied.

Childhood trauma and adult mental disorder: A systematic review and meta‐analysis of longitudinal cohort studies

Evidence for the association between trauma experienced in childhood or adolescence, and the subsequent experience of affective or psychotic mental disorders in adulthood, is reviewed.

The relationship between childhood trauma history and the psychotic subtype of major depression

The relationship between childhood trauma history and the psychotic subtype of major depression is studied in children with a history of abuse or trauma.

Does social defeat mediate the association between childhood trauma and psychosis? Evidence from the NEMESIS‐2 Study

Based on theoretical considerations and animal studies, mediation of ‘social defeat’ (SD) in the association between childhood trauma (CT) and psychosis was investigated.

Stress sensitivity as a putative mechanism linking childhood trauma and psychopathology in youth's daily life

This study aimed to investigate whether CT impacts on youth mental health by modifying sensitivity to stress in daily life by modifying pressure levels in family and social life.

Childhood physical neglect and psychotic experiences: Findings from the National Comorbidity Survey Replication

This study examined the association between childhood physical neglect and psychotic experiences (PEs) in a general population sample and found no link between physical abuse and psychosis.

Gender Differences in the Physical and Psychological Manifestation of Childhood Trauma and/or Adversity in People with Psychosis

The author’s aim has been to contribute towards the humanizing of science by promoting an awareness of the role that science plays in the human experience and in particular in the development of science fiction.

Young people at risk of psychosis: a user‐led exploration of interpersonal relationships and communication of psychological difficulties

Experiences and perceptions of interpersonal relationships and interpersonal communication among young people at risk of psychosis are qualitatively explored.

Sexual Abuse, Paranoia, and Psychosis A Population-Based Mediation Analysis

Cognitive models propose that psychosis may be consequential to threat beliefs which surface following trauma. This study investigated the mediating effect of paranoid ideation on experiences of se...



Relationships between trauma and psychosis: an exploration of cognitive and dissociative factors

Objective:  There is a growing awareness of the relationship between trauma and psychosis. Studies have found associations between traumatic life experiences and the development of psychosis.

Childhood abuse as a risk factor for psychotic experiences

The hypothesis that individuals from the general population who report childhood abuse are at increased risk of developing positive psychotic symptoms is examined.

Psychological therapy in schizophrenia: what is the evidence?

  • H. Brenner
  • Psychology, Medicine
    Acta psychiatrica Scandinavica. Supplementum
  • 2000
The present contribution provides a critical outline of the current position of psychological therapies in schizophrenia with a focus on the treatment of paranoid schizophrenia.

Early trauma may increase the risk for psychotic experiences by impacting on emotional response and perception of control

Exposure to early trauma may increase the risk of dysfunctional responses to anomalous psychotic experiences resulting in psychotic symptom formation, according to the authors.

Post‐traumatic stress disorder: a review of psychobiology and pharmacotherapy

The literature on the psychobiology and pharmacotherapy of PTSD is reviewed to assess the role of drugs and alcohol in the development of post-traumatic stress disorder.

Gender aspects in schizophrenia: bridging the border between social and biological psychiatry

It is shown that gender differences in mental diseases are a valuable paradigm for research into the interplay between biological and psychosocial factors, not only regarding pathogenetic mechanisms, but also concerning therapeutic approaches.

Family work for schizophrenia: practical application

  • J. Leff
  • Medicine, Psychology
    Acta psychiatrica Scandinavica. Supplementum
  • 2000
The evidence for the efficacy, efficiency and effectiveness of family work for schizophrenia is reviewed.

Psychosis: Psychological Approaches and their Effectiveness

  • D. Bhugra
  • Psychology, Medicine
    British Journal of Psychiatry
  • 2002
This book aims to build bridges between professionals from different mental health disciplines who use diverse models of treatment of psychosis with wider attention to a range of psychologically based approaches.

Cognitive Therapy for Psychosis: A Formulation-Based Approach

This paper presents a Cognitive Model of Psychosis, an Introduction to Cognitive Theory and Therapy, and Behavioural Techniques, which outline the techniques used in Therapy to treat Psychosis.

Schneiderian symptoms and childhood trauma in the general population.