Childhood stroke at three years of age with transient protein C deficiency, familial antiphospholipid antibodies and F. XII deficiency--a family study.

@article{Korte1994ChildhoodSA,
  title={Childhood stroke at three years of age with transient protein C deficiency, familial antiphospholipid antibodies and F. XII deficiency--a family study.},
  author={Wolfgang C Korte and Helga Otremba and Sabine Lautenschl{\"a}ger - Peiter Peter Lutz and Renata Flury and Laura Schmid and Markus Weissert},
  journal={Neuropediatrics},
  year={1994},
  volume={25 6},
  pages={290-4}
}
The unusual case of a boy with a stroke occurring at three years of age, transient reduction in protein C activity and high concentrations of antiphospholipid antibodies (APA) is described. APA or Lupus Anticoagulant (LA) were found in 7 of 11 relatives studied out of three different generations. In addition, antigenic Factor (F) XII deficiencies or borderline values were found in the propositus and 2 relatives. Evidence for F. XII inhibitors was found in the propositus, one of his brothers and… CONTINUE READING