Childhood rhabdomyosarcoma metastatic to bone marrow presenting with disseminated intravascular coagulation and acute tumour lysis syndrome: review of the literature apropos of two cases

@inproceedings{Bien2010ChildhoodRM,
  title={Childhood rhabdomyosarcoma metastatic to bone marrow presenting with disseminated intravascular coagulation and acute tumour lysis syndrome: review of the literature apropos of two cases},
  author={Ewa Bien and Lucyna Maciejka-Kapuścińska and Maciej Niedzwiecki and Joanna Stefanowicz and Anna Szolkiewicz and Malgorzata Anna Krawczyk and Jadwiga Maldyk and Ewa Izycka-Swieszewska and Beata Tokarska and Anna Balcerska},
  booktitle={Clinical & Experimental Metastasis},
  year={2010}
}
The paper presents diagnostic and therapeutic difficulties in two adolescents with widespread rhabdomyosarcoma (RMS) presenting with severe haemorrhages resulting from disseminated intravascular coagulation (DIC) and with laboratory features of acute tumour lysis syndrome (ATLS). Other published cases of childhood RMS with DIC at admission have been listed and reviewed. It has been concluded that the clinical picture of a widespread RMS in children may resemble acute hematologic malignancy and… CONTINUE READING
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