Childhood psychosocial stressors and adult onset arthritis: broad spectrum risk factors and allostatic load.

Abstract

Neural, endocrine, and immune stress mediators are hypothesized to increase risks of diverse chronic diseases, including arthritis. Retrospective data from the World Mental Health Surveys (N=18,309) were employed to assess whether adult onset of arthritis was associated with childhood adversities and early onset psychological disorder. Cox proportional… (More)
DOI: 10.1016/j.pain.2009.01.034

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