Childhood neurobehavior disinhibition amplifies the risk of substance use disorder: interaction of parental history and prenatal alcohol exposure.

@article{Chapman2007ChildhoodND,
  title={Childhood neurobehavior disinhibition amplifies the risk of substance use disorder: interaction of parental history and prenatal alcohol exposure.},
  author={Kim L Chapman and Ralph E. Tarter and Levent Kirisci and Marie D. Cornelius},
  journal={Journal of developmental and behavioral pediatrics : JDBP},
  year={2007},
  volume={28 3},
  pages={219-24}
}
OBJECTIVE This investigation examined the influence of parental substance use disorder (SUD) and mother's alcohol consumption during pregnancy on neurobehavior disinhibition (ND) measured in 10- to 12-year-old children. The extent to which ND predicted SUD outcome 7 to 9 years later was also determined. METHODS SUD was documented in each parent and as the outcome variable in their 19-year-old sons. Average daily alcohol consumption during the mother's pregnancy was recorded using a structured… CONTINUE READING

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