Childhood immune thrombocytopenic purpura: diagnosis and management.

  title={Childhood immune thrombocytopenic purpura: diagnosis and management.},
  author={Victor S. Blanchette and P H B Bolton-Maggs},
  journal={Pediatric clinics of North America},
  volume={55 2},
  pages={393-420, ix}
Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by a low circulating platelet count caused by destruction of antibody-sensitized platelets in the reticuloendothelial system. ITP can be classified as childhood versus adult, acute versus chronic, and primary versus secondary. Persistence of thrombocytopenia defines the chronic form of the disorder. Secondary causes of ITP include collagen vascular disorders, immune deficiencies, and some chronic infections. This… CONTINUE READING