Childhood growth hormone deficiency, bone density, structures and fractures: scrutinizing the evidence.

@article{Hgler2010ChildhoodGH,
  title={Childhood growth hormone deficiency, bone density, structures and fractures: scrutinizing the evidence.},
  author={Wolfgang H{\"o}gler and N. P. Shaw},
  journal={Clinical endocrinology},
  year={2010},
  volume={72 3},
  pages={281-9}
}
Childhood-onset growth hormone deficiency (GHD) is frequently perceived to cause low bone density, fractures and osteoporosis. This article critically reviews the evidence behind these perceptions. Inherent limitations of current bone imaging techniques have caused many artefacts and misconceptions about bone density and structure. Using appropriate size-corrections, bone density is normal in children and adults with isolated GHD. Cortical density, trabecular density and trabecular volume are… CONTINUE READING

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