Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study

@article{Hayden2018ChildhoodAI,
  title={Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study},
  author={Lystra P. Hayden and Michael H. Cho and Benjamin A. Raby and Terri H. Beaty and Edwin K. Silverman and Craig P. Hersh},
  journal={Respiratory Research},
  year={2018},
  volume={19}
}
BackgroundChildhood asthma is strongly influenced by genetics and is a risk factor for reduced lung function and chronic obstructive pulmonary disease (COPD) in adults. This study investigates self-reported childhood asthma in adult smokers from the COPDGene Study. We hypothesize that childhood asthma is associated with decreased lung function, increased risk for COPD, and that a genome-wide association study (GWAS) will show association with established asthma variants.MethodsWe evaluated… Expand
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