Childhood acute lymphoblastic leukemia in the age of genomics.

  title={Childhood acute lymphoblastic leukemia in the age of genomics.},
  author={William L Carroll and Deepa Bhojwani and D Min and Naomi Moskowitz and Elizabeth A. Raetz},
  journal={Pediatric blood & cancer},
  volume={46 5},
The recent sequencing of the human genome and technical breakthroughs now make it possible to simultaneously determine mRNA expression levels of almost all of the identified genes in the human genome. DNA "chip" or microarray technology holds great promise for the development of more refined, biologically-based classification systems for childhood ALL, as well as the identification of new targets for novel therapy. To date gene expression profiles have been described that correlate with… CONTINUE READING


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