Child-parent screening for familial hypercholesterolaemia: screening strategy based on a meta-analysis.

  title={Child-parent screening for familial hypercholesterolaemia: screening strategy based on a meta-analysis.},
  author={David S Wald and Jonathan P. Bestwick and Nicholas J Wald},
  volume={335 7620},
OBJECTIVE To develop a population screening strategy for familial hypercholesterolaemia. DESIGN Meta-analysis of published data on total and low density lipoprotein (LDL) cholesterol in people with and without familial hypercholesterolaemia according to age. Thirteen studies reporting on 1907 cases and 16 221 controls were used in the analysis. Included studies had at least 10 cases and controls with data on the distribution of cholesterol in affected and unaffected individuals. MAIN… CONTINUE READING
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