Chikungunya virus isolates with/without A226V mutation show different sensitivity to IFN-a, but similar replication kinetics in non human primate cells.

Abstract

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus responsible for the first autochthonous Italian outbreak in 2007. A226V mutation in E1 has been associated with enhanced replication in A. albopictus vector. Possible involvement of this mutation in enhanced infection capability in primate cells and sensitivity to exogenous interferon (IFN)-a… (More)

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@article{Bordi2011ChikungunyaVI, title={Chikungunya virus isolates with/without A226V mutation show different sensitivity to IFN-a, but similar replication kinetics in non human primate cells.}, author={Licia Bordi and Silvia Meschi and Marina Selleri and Eleonora Lalle and Concetta Castilletti and Fabrizio Carletti and Roberta Chiappini and Antonino Di Caro and Maria Rosaria Capobianchi}, journal={The new microbiologica}, year={2011}, volume={34 1}, pages={87-91} }