Chicken soup inhibits neutrophil chemotaxis in vitro.

  title={Chicken soup inhibits neutrophil chemotaxis in vitro.},
  author={Barbara O Rennard and Ronald F. Ertl and G L Gossman and Richard A. Robbins and Stephen I. Rennard},
  volume={118 4},
Chicken soup has long been regarded as a remedy for symptomatic upper respiratory tract infections. As it is likely that the clinical similarity of the diverse infectious processes that can result in "colds" is due to a shared inflammatory response, an effect of chicken soup in mitigating inflammation could account for its attested benefits. To evaluate this, a traditional chicken soup was tested for its ability to inhibit neutrophil migration using the standard Boyden blindwell chemotaxis… 

Figures and Tables from this paper

Non-hydrolyzed in digestive tract and blood natural L-carnosine peptide (“bioactivated Jewish penicillin”) as a panacea of tomorrow for various flu ailments: signaling activity attenuating nitric oxide (NO) production, cytostasis, and NO-dependent inhibition of influenza virus replication in macroph
The types of protection of carnosine in its bioavailable non-hydrolyzed forms in formulations are considered against reactive oxygen radical species-dependent injury, peroxynitrite damage, and other types of viral injuries in which impaired immune responses to viral pathogens are usually involved.
How to Avoid Coronavirus (COVID-19) or Relief it is Symptoms by Natural Products
The antiviral potencies of some natural product that will help to overcome or relief bad symptoms of coronaviruses are addressed.
Management of the Virulent Influenza Virus Infection by Oral Formulation of Nonhydrolized Carnosine and Isopeptide of Carnosine Attenuating Proinflammatory Cytokine-Induced Nitric Oxide Production
The authors revealed the protection that carnosine and its bioavailable nonhydrolized forms provide against peroxynitrite damage and other types of viral injuries in which immunologic interactions are usually involved.
Mechanisms of Leukocyte Sequestration in Inflamed Lungs
Neutrophils released from the bone marrow traffic first through the pulmonary microvasculature, and the phenotype of these newly released neutrophils impacts pulmonary host defense.
Enriched Chicken Bone Broth as a Dietary Supplement Reduces Nociception and Sensitization Associated with Prolonged Jaw Opening.
Evidence is provided that ECBB attenuates nociception and expression of the pro-inflammatory protein PKA and thus may be beneficial as a nutraceutical supplement to manage inflammatory pain associated with TMD.
Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials
This screening approach succeeded in finding broths with activity against malaria parasite in vitro growth, arising from complex vegetable and/or meat-based broths, representing a successful child education exercise, in teaching about the interface between natural remedies, traditional medicine and evidence-based drug discovery.
Is there a potential application of a fermented nutraceutical in acute respiratory illnesses? An in-vivo placebo-controlled, cross-over clinical study in different age groups of healthy subjects.
FPP supplementation during 1 month resulted in higher salivary IgA and increase in phase II and SOD enzyme expression, i.e the most important antioxidant in the respiratory tract, and the biological significance of these effects remains to be demonstrated in longer clinical trials.
Immuno-Boosters as Health Accelerants to Tackle Viral Infections
This audit article gives a general view about some significant way of life and food propensities that support resistance.
[The impact of viruses in lower respiratory tract infections of the adult. Part III: therapy and prevention].
The present 3 (rd) part deals with therapy for and prevention of viral LRTI, an introduction to the frequently found viruses, pathogenesis, and diagnostic procedures as well as common viral infections of the lower respiratory tract.
Revealing the Secret of Soups' Healing Power: Nanostructures and Their Functions
The artificially formed nanoparticles, consisting the purified glycated polyphenol oxidase, provided the first direct evidence of encapsulation and target delivery capacity of the soup nanostructure, indicating that the functional and toxicological analysis of soups as either food or medicine should include the vital impacts of nanostructures.


Rhinovirus stimulation of interleukin-8 in vivo and in vitro: role of NF-κB.
It is demonstrated that IL-8 is present in normal nasal secretions and that the levels ofIL-8 are further increased after RV infection, and that RVs are potent stimulators of IL- 8 production and that this induction is mediated, at least in part, by an NF-κB-dependent transcriptional activation pathway.
Rhinovirus infection induces mucus hypersecretion.
In addition to promoting plasma exudation, rhinovirus hanks infection increases IL-8 and gel-phase mucin secretion, which may contribute to a progression from watery rhinorrhea to mucoid discharge, with mild neutrophilic infiltration during the common cold.
Neutrophil activation by inflammatory microcrystals of monosodium urate monohydrate utilizes pertussis toxin-insensitive and -sensitive pathways.
Mechanisms of neutrophil activation by monosodium urate crystals appear to be heterogeneous in comparison with activation by formylated peptides and there is no absolute requirement for PT-sensitive membrane G proteins in neutrophIL responsiveness to urates.
Role of nasal interleukin-8 in neutrophil recruitment and activation in children with virus-induced asthma.
It is suggested that IL-8 might provide a target for therapeutic intervention in virus-induced respiratory diseases and correlate with increased nasal aspirate neutrophil myeloperoxidase levels and upper respiratory symptom severity.
New antiasthmatic drugs from traditional medicine?
  • W. DorschH. Wagner
  • Medicine, Biology
    International archives of allergy and applied immunology
  • 1991
Hitherto unknown alkaloids from Adhatoda vasica showed pronounced protection against allergen-induced bronchial obstruction in guinea pigs and Histamine release in vitro was inhibited by other compounds of the plant extract yet to be identified.
Chicken soup or laetrile--which would you prescribe?
  • A. Soffer
  • Medicine
    Archives of internal medicine
  • 1977
Complications in a 40-year-old male physician who declined further chicken soup after initial symptomatic improvement of his pneumococcal pneumonia are described, with a severe relapse five days later.
Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds.
Investigation of the potential involvement of interleukin-1 in the pathogenesis of experimental rhinovirus colds found that most activity in lavages from infected subjects was IL-1 beta, consistent with the hypothesis thatIL-1 could contribute to the pathogenic of rhinOVirus infections.
Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells.
A potential role for neutrophil proteases in the pathogenesis of increased and abnormal submucosal gland secretions in diseases associated with inflammation and neutrophils infiltration of the airways is suggested.
Association between interleukin-8 concentration in nasal secretions and severity of symptoms of experimental rhinovirus colds.
In infected subjects, there was significant rank correlation between nasal obstruction severity, rhinorrhea severity, and nasal-wash albumin concentrations and the change in IL-8 concentration from baseline on days 2-4 after virus challenge.