Chicken recombinant antibodies against infectious bursal disease virus are able to form antibody-virus immune complex.

@article{Ignjatovic2006ChickenRA,
  title={Chicken recombinant antibodies against infectious bursal disease virus are able to form antibody-virus immune complex.},
  author={Jagoda Ignjatovic and George Gould and Lee Trinidad and Sandra I. Sapats},
  journal={Avian pathology : journal of the W.V.P.A},
  year={2006},
  volume={35 4},
  pages={293-301}
}
Virus particles exposed to specific anti-virus antibodies result in the formation of immune complexes (Icx). Recent vaccination strategies have employed this feature, and an infectious bursal disease virus (IBDV) vaccine based on Icx has been released and is expected to replace conventional IBDV vaccines. We evaluated whether chicken recombinant antibodies (rAb) specific for IBDV, rather than conventional chicken anti-IBDV sera, could be used to generate Icx. Out of 14 rAb expressed as soluble… CONTINUE READING

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