Chicken ileal bile-acid-binding protein: a promising target of investigation to understand binding co-operativity across the protein family.

@article{Guariento2009ChickenIB,
  title={Chicken ileal bile-acid-binding protein: a promising target of investigation to understand binding co-operativity across the protein family.},
  author={Mara Guariento and Michael Assfalg and Serena Zanzoni and Dimitrios Fessas and Renato Longhi and Henriette Molinari},
  journal={The Biochemical journal},
  year={2009},
  volume={425 2},
  pages={
          413-24
        }
}
Protein-bile acid interactions are crucial microscopic events at the basis of both physiological and pathological biochemical pathways. BABPs (bile-acid-binding proteins) are intracellular transporters able to bind ligands with different stoichiometry, selectivity and co-operativity. The molecular determinants and energetics of interaction are the observables that connect the microscopic to the macroscopic frameworks. The present paper addresses the study and proposes a mechanism for the multi… CONTINUE READING

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