Chicken homeobox gene Prox 1 related to Drosophila prospero is expressed in the developing lens and retina.

@article{Tomarev1996ChickenHG,
  title={Chicken homeobox gene Prox 1 related to Drosophila prospero is expressed in the developing lens and retina.},
  author={Stanislav I. Tomarev and Olof Sundin and Sharmila Banerjee-Basu and Melinda K. Duncan and J. M. Yang and Joram Piatigorsky},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1996},
  volume={206 4},
  pages={354-67}
}
Prox 1 is the vertebrate homolog of Drosophila prospero, a gene known to be expressed in the lens-secreting cone cells of fly ommatidia. Chicken Prox 1 cDNAs were isolated from 14 day embryonic chicken lenses, and a complete open reading frame encoding an 83 kDa protein was elucidated. The homeodomains of chicken and mouse Prox 1 are identical at the amino acid level and are 65-67% similar to the homeodomains of Drosophila and C. elegans prospero. The homology between these proteins extends… CONTINUE READING
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