Chicken-embryo fibroblasts produce two types of interferon upon stimulation with Newcastle disease virus.

@article{Heller1997ChickenembryoFP,
  title={Chicken-embryo fibroblasts produce two types of interferon upon stimulation with Newcastle disease virus.},
  author={Elimelech Dan Heller and Alon M Levy and R Vaiman and Boris Schwartsburd},
  journal={Veterinary immunology and immunopathology},
  year={1997},
  volume={57 3-4},
  pages={289-303}
}
Controversy has long surrounded the question of whether chickens, like mammals, can produce two types of interferon (IFN). Recently, type-I and type-II chicken IFNs have been cloned. Our study focuses on the further characterization of native fibroblast and spleen IFNs and shows that chicken embryo fibroblasts (CEFs) produce a mixture of type-I and type-II… CONTINUE READING